TY - JOUR A1 - Joseph, Adejoke A1 - Joseph, Oluyemi A1 - Olokoba, Bukola A1 - Olatunji, Olatunji T1 - Chronicles of challenges confronting HIV prevention and treatment in Nigeria Y1 - 2020/9/1 JF - Port Harcourt Medical Journal JO - Port Harcourt Med J SP - 100 EP - 113 VL - 14 IS - 3 UR - https://www.phmj.org/article.asp?issn=0795-3038;year=2020;volume=14;issue=3;spage=100;epage=113;aulast=Joseph DO - 10.4103/phmj.phmj_3_20 N2 - Background: Antiretroviral therapy reduces mortality and morbidity amongst people living with human immunodeficiency virus (HIV)/AIDS, improves their quality of life and reduces the potential to infect others. The goal of National Agency for the Control of AIDS is to achieve and sustain an AIDS-free Nigeria by 2030 hinged on its strategic framework. Achieving this goal is threatened by certain identified challenges. Aim: This study is to review the contents of the national HIV and AIDS strategic framework in a bid to identify the challenges confronting its full implementation in the management of HIV in Nigeria. Methods: Several published articles on HIV prevalence, factors influencing trend and spread, and sociodemographics of the affected were reviewed as well as three federal government of Nigeria national HIV and AIDS strategic framework. Articles were sourced from online indexes such as Medline; sampling about 60 peer-reviewed articles from which information relevant to the topic were retrieved. Publication by relevant bodies on HIV and AIDS was likewise reviewed, and relevant information was retrieved from them. Results: Challenges identified include AIDS-related stigmatisation and discrimination, socio-cultural norms and practices, especially denial of women to inheritance and widow inheritance with its resultant feminisation of poverty and female genital mutilation, reduced funding following the withdrawal of donor agencies, anti-Lesbian, Gay, Bisexual, Transgender and Queer bias, bureaucratic and structural problems, as well as negative attitude of healthcare professionals. Conclusion: The study concludes that achieving an AIDS-free Nigeria with zero new infection and zero. AIDS-related stigmatisation by 2030 will require mitigating against the aforementioned challenges. ER -